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🟥 NINERS RISING: 49ers Dominate Cardinals 41:22 — Brock Purdy and McCaffrey Shine Bright in Arizona!

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🟥 NINERS RISING: 49ers Dominate Cardinals 41:22 — Brock Purdy and McCaffrey Shine Bright in Arizona!

Glendale, Arizona – November 16, 2025
Back after a six-game absence, Brock Purdy turned State Farm Stadium into his personal stage, leading the San Francisco 49ers to a commanding 41:22 win over the Arizona Cardinals. The victory lifts the Niners to 7:4, strengthening their position in the NFC playoff race.


🔥 GAME SUMMARY

Just 16 seconds into the game, Skyy Moore’s 98-yard kickoff return set up a 1-yard TD rush by Christian McCaffrey. Less than six minutes in, the 49ers already had two touchdowns — something they hadn’t done in back-to-back games since 2000.

Brock Purdy (19/26, 200 yards, 3 TDs) was calm and clinical, tossing two touchdown passes to George Kittle, pushing their career total to 23 TD connections, surpassing the legendary Steve Young and Brent Jones duo. McCaffrey was unstoppable again, scoring three total TDs (2 rushing, 1 receiving) and tallying 18 individual points.

The 49ers defense made timely plays:
Two interceptions by Malik Mustapha and Deommodore Lenoir (64-yard return)
• A crucial goal-line fumble forced by Upton Stout and recovered by Keion White

Despite QB Jacoby Brissett breaking the NFL single-game record with 47 completions, the Cardinals self-destructed with 17 penalties – the most in franchise history – costing them over 120 yards and crushing any momentum.


5 TAKEAWAYS FOR THE FAITHFUL

  1. 🏃‍♂️ Skyy Moore exploded with a 98-yard opening return

  • 🧠 Brock Purdy returned with confidence – efficient, mistake-free

  • 💥 New franchise record for Purdy–Kittle – 23 TDs together

  • 🚀 McCaffrey remains unstoppable – extends historic TD streak to 17 games

  • 🛡 Defense delivered – 3 takeaways including a clutch goal-line stand


  • 📅 UP NEXT

    49ers vs. Panthers (Monday Night Football, November 24, 2025 – Levi’s Stadium)
    Goal: Secure a third straight win and keep pace atop the NFC


    📢 MESSAGE TO THE NINERS FAITHFUL

    We stormed through the Arizona desert. Now it’s time to turn Levi’s Stadium into an unbreakable fortress
    🔥 Purdy is back. McCaffrey is a machine. The defense is locked in
    ⏳ The playoffs are approaching. We are ready

     

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