Bills vs Chiefs matchups: Which team has edge at each position in Kansas City Chiefs vs. Buffalo Bills showdown

The highly anticipated Kansas City Chiefs vs Buffalo Bills matchup in NFL Week 9 (2025) is shaping up to be one of the biggest games of the season.
Once again, Patrick Mahomes and Josh Allen will face off in a battle that could define the AFC playoff picture. Here’s a complete position-by-position analysis to see which team truly has the upper hand before kickoff.

Quarterback: Patrick Mahomes vs Josh Allen

Josh Allen’s athleticism and power are undeniable, but Patrick Mahomes remains the most consistent and creative quarterback in football.

Edge: Kansas City Chiefs

Running Back: James Cook vs Isiah Pacheco

The Bills’ ground game, led by James Cook, has quietly become one of the league’s most efficient units. Cook ranks near the top in both rushing yards per game and yards per carry.
The Chiefs, meanwhile, still rely heavily on Mahomes’ arm, and the run game has lacked punch.

Edge: Buffalo Bills

Receivers & Tight Ends: Travis Kelce Makes the Difference

Buffalo’s young receivers bring speed and potential, but Travis Kelce remains the most dangerous weapon in this matchup.
With Rashee Rice emerging as a reliable target, the Chiefs continue to dominate on critical third downs.

Edge: Kansas City Chiefs

Offensive Line

Kansas City’s offensive line has been solid and disciplined, keeping Mahomes upright and comfortable.
Buffalo, on the other hand, has battled injuries, forcing Allen to escape the pocket more often than planned.

Edge: Kansas City Chiefs

Defensive Line & Linebackers

The Chiefs’ defense has been elite all season, powered by Chris Jones and a relentless front seven.
The Bills have playmakers of their own but remain inconsistent due to injuries and lineup shuffles.

Edge: Kansas City Chiefs

Secondary

Buffalo’s veteran secondary still performs at a high level, but the Chiefs’ young defensive backs — led by Trent McDuffie and Justin Reid — have been impressive.
This one could go either way depending on turnovers.

Special Teams

While Harrison Butker has been one of the NFL’s most reliable kickers, recent struggles have slightly opened the door for the Bills’ special teams to gain the edge.
Buffalo’s kicker has shown more consistency lately.

Edge: Buffalo Bills

Overall Advantage: Kansas City Chiefs

When all positions are weighed, the Chiefs hold the edge in five categories, while the Bills lead in three.
With Mahomes playing at MVP level and the home-field advantage at Arrowhead Stadium, Kansas City is slightly favored to take this one.

Prediction: Chiefs narrowly defeat Bills in a close game.

Final Thoughts

The Chiefs vs Bills matchup is more than just a regular-season game — it’s a statement battle between two AFC powerhouses.
Mahomes and Allen will once again push each other to the limit, and every snap will matter.
The only question is: Who will make the final play that decides it all?